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Numerous toxicity studies have been done to assess the safety of MSM and doses up to 4,845.6 mg per day (4.8 grams) appear to be safe ( However, some people may experience mild reactions if they are sensitive to MSM, such as stomach issues like nausea, bloating and diarrhea

People with depression often have too much of the chemical glutamate in their systems, and if it goes unchecked, it can damage neurons and reduce your response to depression treatment

White CM, Tai Z, Nuzi K

[DOI] [PMC free article] [PubMed] [Google Scholar] 70.Inokuchi R., Aoki A., Aoki Y., Yahagi N

Adverse-event tables capture what trial staff asked about or participants reported

Perceived exertion as an indicator of somatic stress